Protein
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A new study may explain the variable severity of SARS-CoV-2 from person to person. Using AI-driven machine-learning researchers discovered the virus is broken down into fragments, and this debris resembles peptides that overstimulate the immune system.
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Using a virus-mimicking DNA scaffold instead of the usual protein one to deliver a vaccine to mice not only generated a robust immune response but avoided the off-target effects sometimes seen when proteins are used.
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Researchers have developed a peptide that targets a protein implicated in 75% of human cancers and found that it slowed the proliferation of cancer cells in the lab. It’s the first step towards developing an effective treatment for a range of cancers.
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Researchers have created a ‘two-headed’ drug that prevents the production of the toxic protein linked to Parkinson’s disease before destroying the RNA machinery that makes it. The drug may be a way of slowing or even stopping the disease’s progression.
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Chinese scientists have developed a cost-effective method of converting coal into protein, which they say could feed livestock much more efficiently than natural plants, while using a tiny fraction of the land.
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A study has found that treatment with a ‘chemical chaperone’ reduced the accumulation of protein plaques and restored cognitive functioning in mouse models of Alzheimer’s, which could lead to novel treatments to help treat the debilitating disease.
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Researchers discovered that a modification to the synthetic mRNA used in therapeutics can cause the cell’s machinery to misread its instructions, leading to unintended immune responses. Importantly, they’ve also discovered a solution to the problem.
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Scientists have solved the mystery of which protein triggers the onset of many cases of frontotemporal dementia, paving the way for more effective early diagnosis of the degenerative disease and the development of potentially life-changing treatment.
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A study has found that a protein that normally triggers our immune system to defend against certain viruses plays a pivotal role in exacerbating COPD. The unexpected discovery may lead to new therapeutic approaches for the incurable condition.
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Researchers have uncovered a protein that facilitates the spread of breast cancer cells into healthy tissue. The discovery improves our understanding of the metastatic process and is the first step to developing treatments that target this mechanism.
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Researchers have identified cell-specific proteins in eye fluid and used AI to determine which proteins accelerated aging in particular diseases. The technique may lead to precision treatments and more informed clinical trials.
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A new study has found that light therapy applied to mice during deep sleep increased the brain’s ability to clear away beta-amyloid protein, which may lead to a drug-free, non-invasive treatment for Alzheimer's disease.
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